A randomized, double-blind, placebo-controlled trial in healthy adults has characterized how the body handles mitragynine and its metabolite 7-hydroxymitragynine after encapsulated kratom extract, according to a study in the Journal of Analytical Toxicology. Researchers including Marilyn Huestis gave participants single doses, then 15 consecutive daily
Pennsylvania legislators are weighing proposals that would regulate kratom sales rather than prohibit the plant outright, according to Pennsylvania Capital-Star reporting republished by WESA. The bills with the most momentum would allow natural kratom leaf to be sold to adults 21 and older while banning
A randomized, double-blind, placebo-controlled clinical trial published in Drug Testing and Analysis found that dried kratom leaf powder produced modest, dose-related subjective effects and minimal signs of opioid withdrawal in healthy adults who had never used kratom before. Researchers gave 116 participants either a single
Gov. Kelly Armstrong has signed House Bill 1628, creating North Dakota's first statewide regulatory framework for kratom. The law, effective once administrative rules are finalized, permits natural kratom sales to adults 21 and older while banning synthetic derivatives such as 7-OH, MGM-15, MGM-16, and mitragynine
Indonesia's Kutai Kartanegara district in East Kalimantan is now exporting an estimated 200 to 300 tonnes of kratom every month to buyers in the United States, India, Thailand, and the Czech Republic, according to a report from Indonesia's state news agency, Antara News. Regional secretary
