How Quickly Does Kratom Tolerance Build And How Long To Go Down?
Tolerance is the diminished response of the body to a drug. This occurs when the drug is repeatedly used for a long period. The body adapts to the continued presence of that drug. To achieve the same effect of a drug, the body requires increased dosage as the receptors no longer respond to that drug at small doses. Tolerance develops because the number of receptors decrease or the affinity with which the drug attaches to the receptor decreases. It could also happen due to increased drug metabolism by the liver enzymes.
Same is the case with Kratom. With regular use of Kratom, one starts developing Kratom. The opiate receptors in the central nervous system become desensitized to Kratom. Thus one is forced to take larger doses at regular intervals to achieve desired effects, this further deteriorates the condition, and thus it is a vicious cycle. The brain and body become dependent on larger doses of Kratom. Consumption of larger doses leads to adverse effects on the liver, nervous system and renal system.
How can I avoid tolerance?
To avoid tolerance from Kratom, you need to follow some very easy steps;
1. Strain rotation: You need to start mixing up your Kratom routine. If you usually use Red Maeng Da, switch over to Green Malay now and then. If you make Kratom tea, start taking it with juice or try a tincture. Just avoid a static Kratom routine.
2. Avoid using Kratom two days in a row.
3. Do not use Kratom more than twice in a week.
4. Do not use Kratom potentiators or other opiate adjuncts: This increases the receptor desensitization and enhances build up of tolerance.
5. Take notes about your Kratom usage. Mention the dose and the strain used to keep a check on your Kratom habits.
6. It’s a good idea to try Kratom blends. Strains that have sedating effects like Red Bali can be mixed with Maeng Da to produce a balanced effect. This way not only you avoid tolerance, but you enjoy the different Kratom combinations and their effects.
7. Take less kratom throughout the day.
8. Also space your doses further than when you usually take kratom. This is done to avoid the stability of the alkaloids in the brain. If it reaches one stable level, then tolerance is more likely to occur.
Tolerance slowing supplements
Certain supplements slow down the buildup of tolerance on opiate receptors. These supplements are NMDA antagonists, a receptor site that is responsible for the development of Kratom tolerance.
One of the best NMDA antagonists is magnesium. Other is Dextromethorphan which is a cough syrup. However, it is suggested not to use these supplements regularly as it can have adverse health effects.